Table 2

The most highly significant canonical pathway assignments for the set of smoking-correlated genes

Canonical pathway

P-value

Number of genes

Natural killer cell signaling

7.9 × 10^-7

11

CTLA4 Signaling in cytotoxic T lymphocytes

1.2 × 10^-4

8

SAPK/JNK signaling

5.7 × 10^-3

6

Xenobiotic metabolism signaling

5.9 × 10^-3

10

Metabolism of xenobiotics by cytochrome P450

9.6 × 10^-3

4

Charlesworth et al. BMC Medical Genomics 2010 3:29   doi:10.1186/1755-8794-3-29