Additional file 1.
Coherence of RAS pathway signatures. Correlation plots showing the relationship between the "UP" and "DOWN" arms of various RAS pathway signatures. A. Bild et al , B. Sweet-Cordero et al , C. Blum et al , D. The ras pathway signature described in this publication. The Y-axis shows the mean log(10) ratio of the genes within the "DOWN" arm of a signature, and the X-axis shows the mean log(10) ratio of the genes within the "UP" arm of a signature. Each dot represents a tumor in the ExpO lung dataset. If a signature is coherent, a pattern of anti-correlation is expected.
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Loboda et al. BMC Medical Genomics 2010 3:26 doi:10.1186/1755-8794-3-26