Tests for association under peak areas of linkage in African American [A] and European American [B] pedigrees selected for increased CAD risk. Significance plotted as -log10(p-value) against chromosomal distance for each factor with suggestive or significant linkage to the specific chromosome region from Tables 3 and 4. Region-specific Bonferroni thresholds are indicated by horizontal blue lines specific to each region (defined as 0.05/n; where n = number of SNPs tested in a region of +/- 5 Mb on either side of the linked STR).
Mathias et al. BMC Medical Genomics 2010 3:22 doi:10.1186/1755-8794-3-22