AML subgroup analysis. Hierarchical clustering revealed gene expression profiles that strongly coincide with AML subgroups according to secondary genetic aberrations and the FAB classification. The agreement between the clustering and the classification with respect to genetic aberations (inv(16) and t(8,21)) and the FAB (French American British) classification is displayed by confusion matrices. The overall survival times of the subgroups are shown in an eventchart. The chromosome view displays the relative frequencies of genomic variations located at chromosome 16.
Gribov et al. BMC Medical Genomics 2010 3:21 doi:10.1186/1755-8794-3-21