Table 4 |
|||||||||||
|
Graffi-virus integration sites in the megakaryoblastic leukaemias |
|||||||||||
|
Sample |
Chromosome |
Genome |
Upstream genes* |
Integra-tion within a gene |
Downstream genes* |
||||||
|
|
|||||||||||
|
gene 1 |
kb |
gene 2 |
kb |
gene 1 |
kb |
gene 2 |
kb |
||||
|
|
|||||||||||
|
Mk1 |
1D |
93018002 |
Gm817 |
17 |
Lrrfip1 |
60 |
Ramp1** |
Ube2f |
95 |
Scly |
130 |
|
1G2 |
153451217 |
Rnf2 |
188 |
1190005F20Rik |
230 |
Niban |
Edem3 |
92 |
Q8K3Do |
199 |
|
|
4B1 |
41816941 |
2310028H24Rik |
133 |
1700066J25Rik |
138 |
Dnaic1 |
Cntfr |
29 |
Dcnt3 |
86 |
|
|
5E 1 |
75741720 |
Pdgfra |
216 |
Gsh2 |
382 |
- |
Kit** |
114 |
Kdr |
472 |
|
|
6F3 |
128801887 |
Klrb1b |
10 |
Clec2h |
159 |
- |
Clec21 |
50 |
Klrb1f |
208 |
|
|
6G1 |
135264443 |
Gsg1 |
61 |
Hebp1) |
130 |
- |
Pbp2 |
10 |
Dynlt1 |
50 |
|
|
11B4 |
70471623 |
Pfn1** |
0.8 |
Rnf167 |
4 |
- |
Eno3 |
1.7 |
Spag7 |
8.2 |
|
|
11B5 |
80139013 |
Rhot1 |
55 |
Rnf135 |
123 |
Rhbd13 |
Zfp207 |
60 |
Psmd11 |
105 |
|
|
15D3 |
62283939 |
Pvt1 |
211 |
Myc** |
463 |
- |
- |
||||
|
15F2 |
95582212 |
Dbx2 |
100 |
Nell2 |
225 |
- |
- |
Tmem16f |
36 |
||
|
16B3 |
33700976 |
Heg1 |
13 |
Slc12a8 |
118 |
- |
Muc13 |
12 |
Itgb5 ** |
48 |
|
|
Mk2 |
|||||||||||
|
1 E4 |
132543823 |
Pfkb2 |
0.4 |
C4bp |
54 |
- |
Yod1 |
0.8 |
AA986890 |
1 |
|
|
6A3 |
25759728 |
Pot 1a |
14 |
Grp37 |
120 |
- |
- |
- |
|||
|
8 E1 |
123703449 |
Irf8 |
81 |
Cox4i1 |
149 |
- |
Foxf1a** |
269 |
Mthfsd |
280 |
|
|
12C1 |
52786246 |
Hectd1 |
120 |
EG544864 |
35 |
- |
Heatr5a |
11 |
6530401NO4Rik |
124 |
|
|
13D2.3 |
116255725 |
Pelo |
46 |
Itga1 |
33 |
- |
- |
- |
|||
|
Mk3 |
|||||||||||
|
1C5 |
Glrp1 |
146 |
Spp2 |
230 |
- |
Arl14c |
161 |
Sh3bp4 |
413 |
||
|
1F |
139621937 |
- |
- |
Ptprc |
257 |
Atp6v1g3 |
466 |
||||
|
2H3 |
165618991 |
Prkcbp1** |
43 |
Eya2 |
156 |
- |
Ncoa3 |
65 |
Sulf2 |
146 |
|
|
5B1 |
43941 |
Rheb |
23 |
Cryng |
83 |
- |
Prkag2** |
20 |
1500035N22Rik |
144 |
|
|
6D2 |
88086902 |
Rpn1 |
16 |
EG434064 |
115 |
- |
Gata2** |
72 |
Dnajb8 |
100 |
|
|
7B4 |
45356428 |
Bax |
21 |
Flt1 |
28 |
Dhdh |
Nucb1 |
4 |
Tulp2 |
25 |
|
|
7F5 |
144856850 |
Ccnd1** |
107 |
Oraov1 |
167 |
- |
Tpcn2) |
167 |
Mrgprf |
253 |
|
|
13A1 |
3830652 |
Calm13 |
27 |
- |
Calm4 |
6 |
Calm5 |
22 |
|||
|
14C3 |
53491694 |
Prmt5 |
20 |
Rem2 |
57 |
- |
D14Ertd500e |
4 |
Jub |
31 |
|
|
19A |
4301566 |
Ankrd13d |
18 |
Ssh3 |
32 |
Adrbk1** |
Fbxl13 |
15 |
FBXL13 |
15 |
|
|
|
|||||||||||
|
* the 2 most proximal genes located at a maximum distance of 500kb upstream (5') or downstream (3') of the integration site ** genes present in the RTCGD database |
|||||||||||
|
Voisin et al. BMC Medical Genomics 2010 3:2 doi:10.1186/1755-8794-3-2 |
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