Table 1 |
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Information on biological processes based on Gene ontology. |
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Biological Process |
Down-regulated genes |
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Cell communication |
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signal transduction |
FAS, SQSTM1, YWHAZ |
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Transcription |
ARID4A, CALR, MYC, PARP1, RNF10, SQSTM1 |
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Translation |
AARS, RPLP0, RPS17, RPS23 |
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Apoptosis |
CALR |
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induction |
FAS |
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anti-apoptosis |
TPT1, YWHAZ |
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Cell migration |
TMSB4X |
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Cell cycle |
DYNC1H1, MYC, PSMC6 |
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Cell proliferation |
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negative regulation |
GPNMB, LDOC1 |
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positive regulation |
MYC |
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Developmental process |
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epidermis development |
UGCG |
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Response to stimulus |
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defense response |
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inflammatory response |
LTA4H |
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response to stress |
EIF2AK1, SQSTM1 |
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response to oxidative stress |
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response to external stimulus |
EIF2AK1 |
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Transport |
CALR, NDUFA4, SQSTM1 |
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Metabolic process |
COX7C, OLA1, |
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protein metabolic process |
PARP1, SQSTM1, USP9X |
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protein modification process |
GRPEL2, HSP90AB1, PPP2R2A, PRPF4B, USP48 |
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lipid metabolic process |
LTA4H, UGCG |
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DNA repair |
PARP1 |
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RNA processing |
PRPF4B, SF3B1 |
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Cellular homeostasis |
CALR, MYC, RPS17 |
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No classification |
GNB2L1, RCN1 |
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Up-regulated genes |
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Transcription |
ENO1 |
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Translation |
EIF1, TARS |
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Apoptosis |
RTN3 |
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induction |
DAP3 |
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Cell proliferation |
PRDX1 |
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negative regulation |
ENO1 |
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Developmental process |
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organ development |
PRDX1 |
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Response to stimulus |
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response to stress |
EIF1, RTN3 |
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Metabolic process |
PRDX1 |
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protein metabolic process |
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protein modification process |
P4HB |
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nucleic acid metabolic process |
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RNA processing |
USP39 |
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Top down- and up-regulated genes selected by RaSH in Hep-2 samples treated with FCM. |
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Rodrigues-Lisoni et al. BMC Medical Genomics 2010 3:14 doi:10.1186/1755-8794-3-14 |
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