Table 1

Information on biological processes based on Gene ontology.

Biological Process

Down-regulated genes


Cell communication

signal transduction

FAS, SQSTM1, YWHAZ


Transcription

ARID4A, CALR, MYC, PARP1, RNF10, SQSTM1


Translation

AARS, RPLP0, RPS17, RPS23


Apoptosis

CALR

induction

FAS

anti-apoptosis

TPT1, YWHAZ


Cell migration

TMSB4X


Cell cycle

DYNC1H1, MYC, PSMC6


Cell proliferation

negative regulation

GPNMB, LDOC1

positive regulation

MYC


Developmental process

epidermis development

UGCG


Response to stimulus

defense response

inflammatory response

LTA4H

response to stress

EIF2AK1, SQSTM1

response to oxidative stress

response to external stimulus

EIF2AK1


Transport

CALR, NDUFA4, SQSTM1


Metabolic process

COX7C, OLA1,

protein metabolic process

PARP1, SQSTM1, USP9X

protein modification process

GRPEL2, HSP90AB1, PPP2R2A, PRPF4B, USP48

lipid metabolic process

LTA4H, UGCG

DNA repair

PARP1

RNA processing

PRPF4B, SF3B1


Cellular homeostasis

CALR, MYC, RPS17


No classification

GNB2L1, RCN1


Up-regulated genes


Transcription

ENO1


Translation

EIF1, TARS


Apoptosis

RTN3

induction

DAP3


Cell proliferation

PRDX1

negative regulation

ENO1


Developmental process

organ development

PRDX1


Response to stimulus

response to stress

EIF1, RTN3


Metabolic process

PRDX1

protein metabolic process

protein modification process

P4HB

nucleic acid metabolic process

RNA processing

USP39


Top down- and up-regulated genes selected by RaSH in Hep-2 samples treated with FCM.

Rodrigues-Lisoni et al. BMC Medical Genomics 2010 3:14   doi:10.1186/1755-8794-3-14

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