Research article
A taxonomy of epithelial human cancer and their metastases
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* Corresponding author: Olivier Gevaert olivier.gevaert@esat.kuleuven.be
1 Bioinformatics, Department of Electrical Engineering (ESAT/SCD), Katholieke Universiteit Leuven, Belgium
2 Liver Facility and Laboratory of Hepatology, Department of Pathophysiology, Katholieke Universiteit Leuven, Belgium
3 Department of Pathology, University Hospitals Gent, Belgium
BMC Medical Genomics 2009, 2:69 doi:10.1186/1755-8794-2-69
Published: 17 December 2009Additional files
Additional file 1:
Sample list. List of all samples in each of the molecular clusters.
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Additional file 2:
GSEA analysis all clusters. Upregulated gene sets in each cluster vs. the remaining samples according to GSEA analysis.
Format: XLS Size: 1.4MB Download file
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Additional file 3:
Breast cancer clinico-pathological data. Grade, histological distribution and receptor status for the breast subclusters.
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Additional file 4:
Breast signature. Breast signature based on differentially expressed genes between Cluster 1 and Cluster 4 in the breast cluster.
Format: XLS Size: 55KB Download file
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Additional file 5:
GSEA kidney samples. Upregulated gene sets in the primary kidney samples in the Thyroid-Kidney cluster vs. the primary kidney samples in the Kidney cluster according to GSEA analysis.
Format: XLS Size: 147KB Download file
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Additional file 6:
GSEA colon-to-liver metastases. Pathways from the colon-to-liver metastases upregulated either in the colon or in the liver cluster according to GSEA analysis.
Format: XLS Size: 505KB Download file
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Additional file 7:
Tissue specific genes. Comparison of the kidney and liver expression signatures from the TIGER database.
Format: XLS Size: 22KB Download file
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Additional file 8:
Differentially expressed genes in breast cluster. Differentially expressed genes between the lobular primary breast samples and the ductal primary breast samples in the mixed lobular-ductal cluster (Cluster A).
Format: XLS Size: 32KB Download file
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Additional file 9:
DAVID results. DAVID functional enrichment analysis of the Breast signature separately for the genes expressed in Cluster 1, Cluster 4 and the GGI signature.
Format: XLS Size: 386KB Download file
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