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Open Access Highly Accessed Research article

A taxonomy of epithelial human cancer and their metastases

Olivier Gevaert1*, Anneleen Daemen1, Bart De Moor1 and Louis Libbrecht23

Author Affiliations

1 Bioinformatics, Department of Electrical Engineering (ESAT/SCD), Katholieke Universiteit Leuven, Belgium

2 Liver Facility and Laboratory of Hepatology, Department of Pathophysiology, Katholieke Universiteit Leuven, Belgium

3 Department of Pathology, University Hospitals Gent, Belgium

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BMC Medical Genomics 2009, 2:69  doi:10.1186/1755-8794-2-69

Published: 17 December 2009

Additional files

Additional file 1:

Sample list. List of all samples in each of the molecular clusters.

Format: XLS Size: 113KB Download file

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Additional file 2:

GSEA analysis all clusters. Upregulated gene sets in each cluster vs. the remaining samples according to GSEA analysis.

Format: XLS Size: 1.4MB Download file

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Additional file 3:

Breast cancer clinico-pathological data. Grade, histological distribution and receptor status for the breast subclusters.

Format: XLS Size: 30KB Download file

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Additional file 4:

Breast signature. Breast signature based on differentially expressed genes between Cluster 1 and Cluster 4 in the breast cluster.

Format: XLS Size: 55KB Download file

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Additional file 5:

GSEA kidney samples. Upregulated gene sets in the primary kidney samples in the Thyroid-Kidney cluster vs. the primary kidney samples in the Kidney cluster according to GSEA analysis.

Format: XLS Size: 147KB Download file

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Additional file 6:

GSEA colon-to-liver metastases. Pathways from the colon-to-liver metastases upregulated either in the colon or in the liver cluster according to GSEA analysis.

Format: XLS Size: 505KB Download file

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Additional file 7:

Tissue specific genes. Comparison of the kidney and liver expression signatures from the TIGER database.

Format: XLS Size: 22KB Download file

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Additional file 8:

Differentially expressed genes in breast cluster. Differentially expressed genes between the lobular primary breast samples and the ductal primary breast samples in the mixed lobular-ductal cluster (Cluster A).

Format: XLS Size: 32KB Download file

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Additional file 9:

DAVID results. DAVID functional enrichment analysis of the Breast signature separately for the genes expressed in Cluster 1, Cluster 4 and the GGI signature.

Format: XLS Size: 386KB Download file

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