Table 2 |
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|
Top 59 genes differentially expressed in sinonasal adenocarcinomas after two-class comparison analysis |
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|
Accession Number |
Gene Symbol |
Gene annotation |
Fold change (log2) |
|
|
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|
LGALS4 |
Up-regulated genes lectin, galactoside-binding, soluble, 4 (galectin 4) |
3.084 |
|
|
ACS5 |
fatty-acid-Coenzyme A ligase, long-chain 5 |
2.621 |
|
|
COL4A1 |
collagen, type IV, alpha 1 |
1.779 |
|
|
JUN |
v-jun sarcoma virus 17 oncogene homolog (avian) |
1.758 |
|
|
CEACAM8 |
carcinoembryonic antigen-related cell adhesion molecule 8 |
1.732 |
|
|
ADFP |
adipose differentiation-related protein |
1.628 |
|
|
similar to 60 kDa heat shock protein, mitochondrialprecursor (Hsp60) (60 kDa chaperonin) (CPN60) (Heat shock protein60) (HSP-60) |
1.617 |
||
|
CCL20 |
chemokine (C-C motif) ligand 20 |
1.560 |
|
|
TGFBI |
transforming growth factor, beta-induced, 68 kDa |
1.493 |
|
|
COL5A2 |
collagen, type V, alpha 2 |
1.461 |
|
|
SRI |
sorcin |
1.456 |
|
|
ANXA4 |
annexin A4 |
1.434 |
|
|
LDHA |
lactate dehydrogenase A |
1.416 |
|
|
STMN1 |
stathmin 1/oncoprotein 18 |
1.414 |
|
|
PLEKHB2 |
pleckstrin homology domain containing, family B (evectins) member 2 |
1.409 |
|
|
similar to Cytochrome c, somatic (LOC164837), mRNA. |
1.387 |
||
|
MRPL13 |
mitochondrial ribosomal protein L13 |
1.370 |
|
|
HSPD1 |
heat shock 60 kDa protein 1 (chaperonin) |
1.346 |
|
|
YWHAZ |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide |
1.342 |
|
|
ACAA2 |
acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) |
1.335 |
|
|
MRPS35 |
mitochondrial ribosomal protein S35 |
1.329 |
|
|
PCNA |
proliferating cell nuclear antigen |
1.319 |
|
|
CKS2 |
CDC28 protein kinase regulatory subunit 2 |
1.278 |
|
|
TPM3 |
tropomyosin 3 |
1.224 |
|
|
DHRS8 |
dehydrogenase/reductase (SDR family) member 8 |
1.206 |
|
|
CASP6 |
caspase 6, apoptosis-related cysteine protease |
1.194 |
|
|
PAPSS2 |
3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
1.172 |
|
|
similar to cytochrome c (LOC157317), mRNA. |
1.164 |
||
|
ENO1 |
enolase 1, (alpha) |
1.145 |
|
|
similar to cytochrome C, expressed in somatic tissues(LOC128146), mRNA. |
1.133 |
||
|
CKLF |
chemokine-like factor |
1.133 |
|
|
ENO1 |
enolase 1, (alpha) |
1.121 |
|
|
ARPC1B |
actin related protein 2/3 complex, subunit 1B, 41 kDa |
1.114 |
|
|
PPIA |
peptidylprolyl isomerase A (cyclophilin A) |
1.110 |
|
|
CLIC1 |
chloride intracellular channel 1 |
1.095 |
|
|
CYCS |
cytochrome c, somatic |
1.081 |
|
|
XRN2 |
5'-3' exoribonuclease 2 |
1.068 |
|
|
HSPD1 |
heat shock 60 kDa protein 1 (chaperonin) |
1.066 |
|
|
PSMA7 |
proteasome (prosome, macropain) subunit, alpha type, 7 |
1.044 |
|
|
TEBP |
unactive progesterone receptor, 23 kD |
1.037 |
|
|
CBX3 |
chromobox homolog 3 (HP1 gamma homolog, Drosophila) |
1.023 |
|
|
CKS1B |
CDC28 protein kinase regulatory subunit 1B |
1.013 |
|
|
MYCN |
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) |
1.006 |
|
|
Down-regulated genes |
|||
|
CLU |
clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) |
-3.606 |
|
|
S100A2 |
S100 calcium binding protein A2 |
-2.152 |
|
|
AKR1C1 |
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) |
-2.102 |
|
|
PPAP2B |
phosphatidic acid phosphatase type 2B |
-1.966 |
|
|
PPAP2B |
phosphatidic acid phosphatase type 2B |
-1.936 |
|
|
CSRP2 |
cysteine and glycine-rich protein 2 |
-1.916 |
|
|
FBLN1 |
fibulin 1 |
-1.799 |
|
|
CRYAB |
crystallin, alpha B |
-1.590 |
|
|
PTN |
pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1) |
-1.405 |
|
|
TF |
transferrin |
-1.256 |
|
|
SEMA3F |
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
-1.246 |
|
|
KRT5 |
keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types) |
-1.207 |
|
|
PLK2 |
polo-like kinase 2 (Drosophila) |
-1.186 |
|
|
NFIB |
nuclear factor I/B |
-1.149 |
|
|
PDGFRA |
platelet-derived growth factor receptor, alpha polypeptide |
-1.090 |
|
|
MADH1 |
MAD, mothers against decapentaplegic homolog 1 (Drosophila) |
-1.047 |
|
|
|
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|
Tripodi et al. BMC Medical Genomics 2009 2:65 doi:10.1186/1755-8794-2-65 |
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