Table 1

Top-ranking Gene Ontology categories identified by LeFEminer on the normalized index cohorts

Category. Rank

Category. Name

Category. Size


1

carboxylic acid metabolism

138


1

Fatty acid metabolism

47


1

Fatty acid metabolism BioCarta

24


1

MAP00480 Glutathione metabolism GenMAPP

18


5

organic acid metabolism

140


5

aromatic compound catabolism

6


5

MAP00350 Tyrosine metabolism GenMAPP

29


8

oxidoreductase activity, acting on CH-OH group of donors

44


9

aromatic amino acid family catabolism

5


10

electron transporter activity BioCarta

102


11

Cyclic nucleotide-dependent protein kinase activity

4


11

ANDROGEN UP GENES na

56


13

tyrosine catabolism

3


13

Fatty Acid Synthesis BioCarta

14


15

regulation of locomotion

6


16

acetylgalactosaminyltransferase activity

7


16

polypeptide N-acetylgalactosaminyltransferase activity

7


16

MAP00360 Phenylalanine metabolism GenMAPP

16


19

breast cancer estrogen signalling GEArray

92


20

peroxisome

36


20

MAP00512 O Glycans biosynthesis GenMAPP

7


22

amine catabolism

23


22

cAMP-dependent protein kinase activity

4


24

regulation of cell migration

6


24

microtubule cytoskeleton organization and biogenesis

23


24

mitotic spindle checkpoint

2


24

electron transporter activity

114


24

Microbody

36


29

regulation of behaviour

6


29

neuronal lineage restriction

2


Rank determined by p-value and false discovery rate. All categories shown in table were identified with 0% false discovery rate. The Category. Size column lists the number of genes in the pre-defined dataset representative of the GO category.

Sanga et al. BMC Medical Genomics 2009 2:59   doi:10.1186/1755-8794-2-59

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