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Open Access Research article

An assessment of the portability of ancestry informative markers between human populations

Sean Myles1*, Mark Stoneking2 and Nic Timpson34

Author Affiliations

1 Institute for Genomic Diversity, Cornell University, 175 Biotechnology Building, Ithaca, NY 14853-2703, USA

2 Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany

3 Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford, OX3 7BN, UK

4 MRC CAiTE Centre, Department of Social Medicine, University of Bristol, Oakfield House, Oakfield Grove, BS8 2BN, UK

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BMC Medical Genomics 2009, 2:45  doi:10.1186/1755-8794-2-45

Published: 20 July 2009

Additional files

Additional file 1:

Worldwide risk allele frequencies and population differentiation for the 10 BritAIMs. The dbSNP ID is found at the top of each figure. Minor allele frequencies are displayed in the vertical bar chart with sample size in number of individuals to the left. Each box in the 53 × 53 and 7 × 7 matrices represents a pairwise Fst comparison between populations and geographic regions, respectively. The shaded boxes in the matrices indicate which pairwise Fst values are significant compared to the empirical distribution at three P value thresholds (see the boxed-in P value legend of Figure 4).

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