Relapse-free survival from high and low-risk groups according to the proportion of chromosomal amplifications. RFS curves for the 65 lung adenocarcinomas considering high and low-risk groups. High-risk group are those with a high proportion of amplification (above the third quartile, plain line) whereas low-risk group are those with low proportion of amplification (above the third quartile, dash line). These proportions are computed over genomic clones prone to non-random chromosomal event that belong to "exclusively amplified regions" (class 7 as defined in our model).
Broët et al. BMC Medical Genomics 2009 2:43 doi:10.1186/1755-8794-2-43