Table 3

List of 12 candidate genes putatively inactivated by nonsense mutation, including their chromosomal location, the cell line where it was identified and a short description of the gene.

Gene

Location

Cell line

Description


PLA2G4A

1q31.1

GP202

phospholipase A2, group IVA

INHBB

2q14,2

IPA220

Inhibin, beta B

CSTA

3q21.1

GP202

Cystatin A

BMP5

6p12.1

GP202

Bone morphogenetic protein 5

MMP6

7p15.3

GP202

membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)

FOXK1

7p22.1

IPA220

Forkhead box K1

PTPRJ

11p11.2

IPA220

Protein tyrosine phosphatase, receptor type J

KCNMB4

12q15

GP202

Potassium channel, calcium-activated, large conductance, subfamily M, beta member 4

SLITRK6

13q31.1

GP202, IPA220

SLIT and NTRK-like family, member 6

SNN

16p13

IPA220

stannin

TXNL4B

16q22.2

IPA220

Thioredoxin-like 4B

DYM

18q21.1

GP202

dymecelin


Buffart et al. BMC Medical Genomics 2009 2:39   doi:10.1186/1755-8794-2-39

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