Gene expression-based profiles related to survival duration across GBM tumours. A. 377 probesets were used to classify the GBMs available on the U133A and U133 Plus 2.0 arrays, while 177 probesets were used to classify the tumours available on the U95Av2 arrays. The four glioblastoma types: PN: ProNeural (yellow, n = 77), Pro: Proliferative (blue, n = 61), ProMes: Proliferative-Mesenchymal (purple n = 29), and Mes: Mesenchymal (red, n = 100). B. Percent composition of Long (LTS), Medium (MTS), and Short (STS) term survival across the three glioma gene-signature tumour types. Over one-third of PN-classified tumour patients survive over 2 years, while over half of Pro, ProMes, and Mes classified tumour patients succumb in less than 1 year.
Lee et al. BMC Medical Genomics 2008 1:52 doi:10.1186/1755-8794-1-52