Quantitative PCR mapping for the ASMT gene duplication. Quantitative PCR probes were designed to detect copy number changes in ASMTL, P2RY8, CXYorf3 (which overlaps with exon 1 of ASMT), and ASMT (exons 1, 2, 3, 6, 8, 9, and 10). Results for a normal control (white), a subject with ASD but without the duplication (green), a subject with ASD with the duplication (i.e., three copies) (blue), and a subject with ASD with four copies of the region (red) are shown.
Cai et al. BMC Medical Genomics 2008 1:50 doi:10.1186/1755-8794-1-50