Research article
Tiling resolution array CGH and high density expression profiling of urothelial carcinomas delineate genomic amplicons and candidate target genes specific for advanced tumors
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* Corresponding author: Mattias Höglund mattias.hoglund@med.lu.se
1 Department of Clinical Genetics, Lund University Hospital, SE-221 85 Lund, Sweden
2 Department of Urology, Lund University Hospital, SE-221 85 Lund, Sweden
3 Department of Pathology and Cytology, Helsingborg Hospital AB, SE-251 87 Helsingborg, Sweden
4 Department of Oncology, Lund University Hospital, SE-221 85 Lund, Sweden
BMC Medical Genomics 2008, 1:3 doi:10.1186/1755-8794-1-3
Published: 31 January 2008Additional files
Additional file 1:
Clinical data. Data on sex, age, stage, and grade given for each patient as well as which samples were analyzed by expression profiling.
Format: TIFF Size: 16.6MB Download file
Additional file 2:
Array-CGH data. BAC clone, genes, cytoband, start and end of BAC clone are given as well as the gene copy ratios in the individual samples.
Format: DOC Size: 56KB Download file
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Additional file 3:
Correlations between gene copy numbers and gene expression. The correlation between gene copy numbers and gene expression for genes within the 2p25, 6p22, and 8q22 amplicons.
Format: TXT Size: 13MB Download file
Additional file 4:
ID4, E2F3, and CDKLA1 gene expression. Results from Q-PCR analyses of ID4, E2F3, and CDKLA1 gene expression.
Format: XLS Size: 26KB Download file
This file can be viewed with: Microsoft Excel Viewer
Additional file 5:
Homozygous deletions. Table of cytogenetic and Mbp positions, sizes, and included genes in the identified homozygous deletions.
Format: DOC Size: 46KB Download file
This file can be viewed with: Microsoft Word Viewer