BMC Medical Genomics

official impact factor 3.77

Open Access

Tiling resolution array CGH and high density expression profiling of urothelial carcinomas delineate genomic amplicons and candidate target genes specific for advanced tumors

Markus Heidenblad, David Lindgren, Tord Jonson, Fredrik Liedberg, Srinivas Veerla, Gunilla Chebil, Sigurdur Gudjonsson, Åke Borg, Wiking Månsson and Mattias Höglund*

BMC Medical Genomics 2008, 1:3 doi:10.1186/1755-8794-1-3

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Method   Open Access Highly Accessed

Analysis of the copy number profiles of several tumor samples from the same patient reveals the successive steps in tumorigenesis

Eric Letouzé, Yves Allory, Marc A Bollet, François Radvanyi, Frédéric Guyon Genome Biology 2010, 11:R76 (22 July 2010)

TuMult is a method for reconstructing the history of cancer progression from copy number variations in several samples from a patient

Methodology article   Open Access

HAT: Hypergeometric Analysis of Tiling-arrays with application to promoter-GeneChip data

Erdogan Taskesen, Renee Beekman, Jeroen de Ridder, Bas J Wouters, Justine K Peeters, Ivo P Touw, Marcel JT Reinders, Ruud Delwel BMC Bioinformatics 2010, 11:275 (21 May 2010)

Research article   Open Access

Recurrent and multiple bladder tumors show conserved expression profiles

David Lindgren, Sigurdur Gudjonsson, Kowan Jee, Fredrik Liedberg, Sonja Aits, Anna Andersson, Gunilla Chebil, Åke Borg, Sakari Knuutila, Thoas Fioretos, Wiking Månsson, Mattias Höglund BMC Cancer 2008, 8:183 (30 June 2008)

Although recurrent urothelial tumors are unlikely to originate directly from the initial lesion, genome and transcriptome profiling suggests that the gene expression profile is established early in their development and maintained in subsequent tumors.