|
Top coregulated clusters of genes |
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| Human cluster |
Rat cluster |
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|
|
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| Gene Symbol |
Gene Description |
t* |
q** |
t* |
q** |
|
|
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| TXNIP |
thioredoxin interacting protein |
-5.5 |
0.0002 |
-12.5 |
0 |
| RBP1 |
retinol binding protein 1, cellular |
-4.2 |
0.0021 |
-15.1 |
0 |
| IGFBP3 |
insulin-like growth factor binding protein 3 |
-4.6 |
0.0007 |
-10.0 |
0 |
| IFITM3 |
interferon induced transmembrane protein 3 (1–8 U) |
-5.2 |
0.0002 |
-9.0 |
0 |
| DHRS8 |
dehydrogenase/reductase (SDR family) member 8 |
-5.4 |
0.0002 |
-5.6 |
0 |
| LDHB |
lactate dehydrogenase B |
-4.6 |
0.0006 |
-6.1 |
0 |
| LAPTM4B |
lysosomal associated protein transmembrane 4 beta |
-4.5 |
0.0008 |
-8.3 |
0 |
| MUC1 |
mucin 1, transmembrane |
-5.7 |
0.0002 |
-5.2 |
0 |
| SFRP2 |
secreted frizzled-related protein 2 |
-5.4 |
0.0002 |
-5.8 |
0 |
| IFITM1 |
interferon induced transmembrane protein 1 (9–27) |
-4.2 |
0.0019 |
-6.8 |
0 |
| CD74 |
CD74 antigen |
-4.3 |
0.0015 |
-8.2 |
0 |
| LR8 |
LR8 protein |
-3.6 |
0.0076 |
-7.6 |
0 |
| B2M |
beta-2-microglobulin |
-4.1 |
0.0025 |
-8.0 |
0 |
| PPP1R1B |
protein phosphatase 1, regulatory (inhibitor) subunit 1B |
-4.8 |
0.0006 |
-6.1 |
0 |
| PRKACB |
protein kinase, cAMP-dependent, catalytic, beta |
-5.2 |
0.0003 |
-4.2 |
0 |
| TSPAN3 |
tetraspanin 3 |
-4.4 |
0.0014 |
-6.5 |
0 |
| PROM1 |
prominin 1 |
-2.8 |
0.0452 |
-9.0 |
0 |
| TMC4 |
transmembrane channel-like 4 |
-3.8 |
0.0045 |
-8.0 |
0 |
| ITM2C |
integral membrane protein 2C |
-3.0 |
0.0343 |
-8.0 |
0 |
| DHRS3 |
dehydrogenase/reductase (SDR family) member 3 |
-3.6 |
0.0079 |
-5.9 |
0 |
| ITM2B |
integral membrane protein 2B |
-2.5 |
0.0778 |
-9.6 |
0 |
| VIM |
vimentin |
-2.7 |
0.0503 |
-9.6 |
0 |
| NPC2 |
Niemann-Pick disease, type C2 |
-4.0 |
0.0029 |
-6.5 |
0 |
| AXL |
AXL receptor tyrosine kinase |
-4.4 |
0.0012 |
-4.9 |
0 |
| HLA-DRA |
major histocompatibility complex, class II, DR alpha |
-3.3 |
0.0153 |
-8.5 |
0 |
| EEF1A1 |
Eukaryotic translation elongation factor 1 alpha 1 |
-4.1 |
0.0023 |
-5.1 |
0 |
| FOXQ1 |
forkhead box Q1 |
-3.5 |
0.0116 |
-6.1 |
0 |
| IFNGR1 |
interferon gamma receptor 1 |
-2.5 |
0.0745 |
-8.5 |
0 |
| IGFBP7 |
insulin-like growth factor binding protein 7 |
-3.4 |
0.0138 |
-7.2 |
0 |
| RNASET2 |
ribonuclease T2 |
-3.0 |
0.032 |
-7.4 |
0 |
| SAT |
spermidine/spermine N1-acetyltransferase |
-3.7 |
0.0073 |
-7.6 |
0 |
| BHLHB3 |
basic helix-loop-helix domain containing, class B, 3 |
-5.8 |
0.0002 |
-2.3 |
0.04 |
| SELENBP1 |
selenium binding protein 1 |
-4.0 |
0.0033 |
-4.8 |
0 |
| C11orf8 |
chromosome 11 open reading frame 8 |
-5.0 |
0.0004 |
-3.6 |
0 |
| LSP1 |
lymphocyte-specific protein 1 |
-4.9 |
0.0004 |
-2.9 |
0 |
| KRT19 |
keratin 19 |
-3.3 |
0.0 |
-10.1 |
0 |
|
t* Average t-statistic q** Average q-value | |||||
Jelinsky et al. BMC Medical Genomics 2008 1:27 doi:10.1186/1755-8794-1-27 |
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