Figure 4.

Worldwide risk allele frequencies and population differentiation for rs10761659, a SNP associated with Crohn's disease. The vertical bar chart displays risk allele frequencies in each of the populations represented in the CEPH-HGDP panel with sample sizes in number of individuals on the left. The shaded boxes in the 53 × 53 and 7 × 7 matrices show which pairwise Fst values are significant compared to the empirical distribution at three P value thresholds (see the boxed-in P value legend).