Open Access Highly Accessed Research article

The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis

Adam I Riker1*, Steven A Enkemann2, Oystein Fodstad1, Suhu Liu1, Suping Ren1, Christopher Morris1, Yaguang Xi1, Paul Howell1, Brandon Metge1, Rajeev S Samant1, Lalita A Shevde1, Wenbin Li3, Steven Eschrich2, Adil Daud2, Jingfang Ju1 and Jaime Matta4

Author Affiliations

1 Mitchell Cancer Institute-University of South Alabama, 315 North University Boulevard, MSB 2015, Mobile, Alabama 36688, USA

2 H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, Florida 33612, USA

3 Xuanwu Hospital, 45 Changchu St., Xuanwu District, Beijing, 10053, PRoC

4 Department of Pharmacology, Physiology and Toxicology, Ponce School of Medicine. P.O. Box 7004, Ponce, 00732, Puerto Rico

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BMC Medical Genomics 2008, 1:13  doi:10.1186/1755-8794-1-13

Published: 28 April 2008

Additional files

Additional file 1:

Detailed Gene Microarray Analysis and Bioinformatics. This document provides a more detailed and in-depth description of the statistical and biostatistical process involved in the supervised analysis of the generated data. We have also added a description of patient demographics.

Format: DOC Size: 33KB Download file

This file can be viewed with: Microsoft Word Viewer

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Additional file 2:

Final Supervised Gene List. The data in this file describes the following: Supervised Gene list, symbol, GenBank reference ID #, Entrez Med ID #, UniGene ID #, Human Protein Atlas Tissue Staining Link for each gene.

Format: XLS Size: 3.4MB Download file

This file can be viewed with: Microsoft Excel Viewer

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Additional file 3:

Gene Ontology and Biological Processes. This file shows the ontological comparisons of various numbers of genes associated with each biological process between primary and metastatic melanoma.

Format: PDF Size: 18KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data