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This article is part of the supplement: Metabolism, diet and disease

Open Access Oral presentation

A transdisciplinary approach to obesity and cancer: from cells to society

Linda Nebeling

  • Correspondence: Linda Nebeling

Author Affiliations

National Cancer Institute, USA

BMC Proceedings 2012, 6(Suppl 3):O18  doi:10.1186/1753-6561-6-S3-O18

The electronic version of this article is the complete one and can be found online at:

Published:1 June 2012

© 2012 Nebeling; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Oral presentation

The increasing recognition of the complex, multidimensional relationship between excess adiposity and cancer risk, coupled with the high prevalence of obesity in the US, has motivated the scientific community to seek new research models and paradigms. Compared to traditional unidisciplinary research, transdisciplinary research is seen as having the potential to accelerate both discovery and its translation to practice, and eventually policy. In response, the National Cancer Institute (NCI) developed a centers grant mechanism in nutrition, energetics, and physical activity; referred to as the Transdisciplinary Research on Energetics and Cancer (TREC) Initiative ( webcite). These Centers foster collaboration among transdisciplinary teams of scientists with the goal of accelerating progress towards reducing cancer incidence, morbidity and mortality associated with obesity, low levels of physical activity and poor diet. This presentation will review key opportunities in transdisciplinary research, highlight lessons learned and note future challenges.