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BMC Proceedings publishes selected collections of research articles, conference proceedings, reviews and reports as supplements, which are free to access online. All articles published in supplements are subject to peer review; meeting abstracts undergo review and selection by the conference. Find out more about publishing a supplement with BioMed Central.

Volume 5 Supplement 9

Genetic Analysis Workshop 17: Unraveling Human Exome Data

Proceedings

Genetic Analysis Workshop 17

Boston, MA, USA

13-16 October 2010

Edited by S Ghosh, H Bickeböller, J Bailey, JE Bailey-Wilson, R Cantor, W Daw, AL DeStefano, CD Engelman, A Hinrichs, J Houwing-Duistermaat, IR König, J Kent Jr., N Pankratz, A Paterson, E Pugh, Y Sun, A Thomas, N Tintle, X Zhu, JW MacCluer and L Almasy

Conference website

Identifying rare variants from exome scans: the GAW17 experience

Saurabh Ghosh, Heike Bickeböller, Julia Bailey, Joan E Bailey-Wilson, Rita Cantor, Robert Culverhouse, Warwick Daw, Anita L DeStefano, Corinne D Engelman, Anthony Hinrichs, Jeanine Houwing-Duistermaat, Inke R König, Jack Kent, Nan Laird, Nathan Pankratz, Andrew Paterson, Elizabeth Pugh, Brian Suarez, Yan Sun, Alun Thomas, Nathan Tintle, Xiaofeng Zhu, Andreas Ziegler, Jean W MacCluer, Laura Almasy BMC Proceedings 2011, 5(Suppl 9):S1 (29 November 2011)

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Genetic Analysis Workshop 17 mini-exome simulation

Laura Almasy, Thomas D Dyer, Juan Peralta, Jack W Kent, Jac C Charlesworth, Joanne E Curran, John Blangero BMC Proceedings 2011, 5(Suppl 9):S2 (29 November 2011)

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Identifying influential regions in extremely rare variants using a fixed-bin approach

Michael Agne, Chien-Hsun Huang, Inchi Hu, Haitian Wang, Tian Zheng, Shaw-Hwa Lo BMC Proceedings 2011, 5(Suppl 9):S3 (29 November 2011)

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Identification of genes and variants associated with quantitative traits using Bayesian factor screening

Kith Pradhan, Seungtai Yoon, Tao Wang, Kenny Ye BMC Proceedings 2011, 5(Suppl 9):S4 (29 November 2011)

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Genome-wide association analysis of GAW17 data using an empirical Bayes variable selection

Vitara Pungpapong, Libo Wang, Yanzhu Lin, Dabao Zhang, Min Zhang BMC Proceedings 2011, 5(Suppl 9):S5 (29 November 2011)

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A weighted accumulation test for associating rare genetic variation with quantitative phenotypes

Chuanhua Xing, Glen A Satten, Andrew S Allen BMC Proceedings 2011, 5(Suppl 9):S6 (29 November 2011)

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A gene-based approach for testing association of rare alleles

Hongyan Xu, Varghese George BMC Proceedings 2011, 5(Suppl 9):S7 (29 November 2011)

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Population structure analysis using rare and common functional variants

Tesfaye M Baye, Hua He, Lili Ding, Brad G Kurowski, Xue Zhang, Lisa J Martin BMC Proceedings 2011, 5(Suppl 9):S8 (29 November 2011)

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Pairwise shared genomic segment analysis in high-risk pedigrees: application to Genetic Analysis Workshop 17 exome-sequencing SNP data

Zheng Cai, Stacey Knight, Alun Thomas, Nicola J Camp BMC Proceedings 2011, 5(Suppl 9):S9 (29 November 2011)

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Detection of associations with rare and common SNPs for quantitative traits: a nonparametric Bayes-based approach

Lili Ding, Tesfaye M Baye, Hua He, Xue Zhang, Brad G Kurowski, Lisa J Martin BMC Proceedings 2011, 5(Suppl 9):S10 (29 November 2011)

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Successful identification of rare variants using oligogenic segregation analysis as a prioritizing tool for whole-exome sequencing studies

France Gagnon, Nicole M Roslin, Mathieu Lemire BMC Proceedings 2011, 5(Suppl 9):S11 (29 November 2011)

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Evaluation of a LASSO regression approach on the unrelated samples of Genetic Analysis Workshop 17

Wei Guo, Robert C Elston, Xiaofeng Zhu BMC Proceedings 2011, 5(Suppl 9):S12 (29 November 2011)

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Identification of functional genetic variation in exome sequence analysis

Andrew Jaffe, Genevieve Wojcik, Audrey Chu, Asieh Golozar, Ankit Maroo, Priya Duggal, Alison P Klein BMC Proceedings 2011, 5(Suppl 9):S13 (29 November 2011)

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Comparing nominal and real quality scores on next-generation sequencing genotype calls

Alexander H Stram BMC Proceedings 2011, 5(Suppl 9):S14 (29 November 2011)

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Comparison of results from tests of association in unrelated individuals with uncollapsed and collapsed sequence variants using tiled regression

Heejong Sung, Yoonhee Kim, Juanliang Cai, Cheryl D Cropp, Claire L Simpson, Qing Li, Brian C Perry, Alexa JM Sorant, Joan E Bailey-Wilson, Alexander F Wilson BMC Proceedings 2011, 5(Suppl 9):S15 (29 November 2011)

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Enhancing the discovery of rare disease variants through hierarchical modeling

Gary K Chen BMC Proceedings 2011, 5(Suppl 9):S16 (29 November 2011)

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Identifying rare disease variants in the Genetic Analysis Workshop 17 simulated data: a comparison of several statistical approaches

Ruixue Fan, Chien-Hsun Huang, Shaw-Hwa Lo, Tian Zheng, Iuliana Ionita-Laza BMC Proceedings 2011, 5(Suppl 9):S17 (29 November 2011)

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Pathway analysis following association study

Julius S Ngwa, Alisa K Manning, Jonna L Grimsby, Chen Lu, Wei V Zhuang, Anita L DeStefano BMC Proceedings 2011, 5(Suppl 9):S18 (29 November 2011)

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Gene-based partial least-squares approaches for detecting rare variant associations with complex traits

Asuman S Turkmen, Shili Lin BMC Proceedings 2011, 5(Suppl 9):S19 (29 November 2011)

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Incorporating predicted functions of nonsynonymous variants into gene-based analysis of exome sequencing data: a comparative study

Peng Wei, Xiaoming Liu, Yun-Xin Fu BMC Proceedings 2011, 5(Suppl 9):S20 (29 November 2011)

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