Table 2

Average proportion of 200 replicates identifying noncausal variants in traits Q1, Q2, and Q4

Trait

PoR for uncollapsed variants

PoR for collapsed variants

(MAF < 0.01 and nonsynonymous)


TR 10−2

TR 10−7

SLR 10−7

TR 10−2

TR 10−7

SLR 10−7


Q1

9.7 × 10−4

5.5 × 10−6

6.8 × 10−4

1.3 × 10−3

7.3 × 10−6

1.0 × 10−3

Q2

1.3 × 10−3

6.2 × 10−6

3.1 × 10−6

1.7 × 10−3

3.8 × 10−6

2.1 × 10−6

Q4

1.3 × 10−3

3.5 × 10−6

2.0 × 10−7

1.7 × 10−3

3.2 × 10−6

0.0


TR, tiled regression. SLR, simple linear regression. PoR, proportion of 200 replicates. For the tiled regression, 10−2 and 10−7 are the critical values; for the simple linear regression, 10−7 is the significance level.

Sung et al. BMC Proceedings 2011 5(Suppl 9):S15   doi:10.1186/1753-6561-5-S9-S15

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