Table 1

Comparison of mAb production using ATF or TFF system at day 17 with cell densities maintained at 20-30 x 106 cells/mL.

ATF

TFF


Production in harvest (g)

9

7

Yield (production in harvest/total production) (g/g in %)

75

55

Total removal of mAb in cell bleeds/total production (g/g in %)

19

30

Residual mAb mass in bioreactor/total production (g/g in %)

6

15


Clincke et al. BMC Proceedings 2011 5(Suppl 8):P105   doi:10.1186/1753-6561-5-S8-P105

Open Data