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This article is part of the supplement: International Conference on Prevention & Infection Control (ICPIC 2011)

Open Access Poster presentation

Central nervous system infections in postnerosurgical patients

HL Albornoz1*, L Ibias1, A Gadea1, F Porcires1, R Brinckhaus1, N Ramos2 and H Bagnulo1

  • * Corresponding author: HL Albornoz

Author Affiliations

1 Intensive Care Unit, Hospital Maciel, Montevideo, Uruguay

2 Infection Control Commitee, Hospital Maciel, Montevideo, Uruguay

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BMC Proceedings 2011, 5(Suppl 6):P191  doi:10.1186/1753-6561-5-S6-P191

The electronic version of this article is the complete one and can be found online at:

Published:29 June 2011

© 2011 Albornoz et al; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Introduction / objectives

Central nervous system infections in neurosurgical patients (pts) are a seriuos complication with high morbidity and mortality. We describe characteristics of patients and episodes, microorganisms and evolution of neurosurgical pts with meningitis (M) or ventriculitis (V) in one ICU in Uruguay.


Retrospective analysis of neurosurgical pts with M or V in a ten year period (2000-2010). M and V was defined based in cerebrospinal fluid findings (glucose <0.4 g/L, < 40% plasmatic glucose, leucocytes > 50/ mL (>50% neutrophils), lactate > 4 mM/L) and culture (definitive episodes). V required intraventricular procedure or device implantation.


69 pts (47 years, male 69%, SAPS II 33, mechanical ventilation 92%) developed 77 episodes (M 44, V 32). Neurosurgical diseases were trauma (39%), meningeal hemorrhage (20%), intracerebral hemorrhage (17%), intracranial tumor (12%). Cerebrospinal fluid leakage was present in 25%, ventriculostomy in 35% (catheter permanence 6.2 days), subdural catheter in 30% (catheter permanence 4.2 days). Microorganisms were mainly Gram negative bacilli (Acinetobacter sp (20, 26%), Klebsiella sp (7, 9%), Ps aeruginosa (7, 9%), Proteus sp (3, 3.9%), Enterobacter sp (3, 3.9%), S aureus (8, 10.4%), S coagulase negative (6, 7.8%), Enterococcus sp (3, 3.9%), Candida sp (5, 6.5%)). Crude mortality was 29% (20/69).


In a selected group of seriously ill and high risk neurosurgical patients M and V were mainly caused for Gram negative bacilli and had high mortality.

Disclosure of interest

None declared.