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This article is part of the supplement: Proceedings of the International Symposium on Animal Genomics for Animal Health (AGAH 2010)

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Genomic selection for carrier-state resistance in chicken commercial lines

Fanny Calenge1*, Andres Legarra2 and Catherine Beaumont1

Author Affiliations

1 INRA UMR83 Unité de Recherches Avicoles, 37380 Nouzilly, France

2 INRA UR0631 Station d’Amélioration Génétique des Animaux, chemin de Borde-Rouge, 31326 Auzeville, France

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BMC Proceedings 2011, 5(Suppl 4):S24  doi:10.1186/1753-6561-5-S4-S24

Published: 3 June 2011



Salmonella propagation by apparently healthy chicken and subsequent food security concerns could be decreased by the selection and use of chicken lines more resistant to carrier-state. In the present study we applied the first steps of the genomic selection methodology to assess the interest of including genetic markers for the genetic evaluation of hen lines infected with Salmonella Enteritidis.


We studied commercial laying hen lines divergently selected for resistance to Salmonella carrier-state at two different ages. A total of 600 animals were typed with 1536 SNP markers and artificially infected with S. Enteritidis. Phenotypes were collected four weeks (young animals) or five weeks (adults) later. Two types of variance component analyses, including or not including SNP data, were performed and compared. All variance components were estimated by Bayesian methods and Gibbs sampling.


The comparison of both genetic analyses shows that SNP are efficient in capturing genetic variation, although none of them captures a large affect on the traits studied. Average accuracies do not change between analyses, showing that using SNP data does not really increase information.


These preliminary results show that genomic selection for Salmonella carrier-state resistance in laying hens is promising, although a denser SNP coverage of the genome on a higher number of animals is needed to assess its feasibility and efficiency compared to classical pedigree evaluation.