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This article is part of the supplement: Proceedings of the 14th European workshop on QTL mapping and marker assisted selection (QTL-MAS)

Open Access Proceedings

QTLMAS 2010: simulated dataset

Maciej Szydlowski* and Paulina Paczyńska

Author Affiliations

Department of Genetics and Animal Breeding, Poznan University of Life Sciences, Wolynska 33, 60-637 Poznan, Poland

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BMC Proceedings 2011, 5(Suppl 3):S3  doi:10.1186/1753-6561-5-S3-S3

Published: 27 May 2011

Abstract

Background

Objective was to simulate the data for the QTLMAS 2010 Workshop under a model that includes major additive, epistatic and parent-of-origin effects.

Results

Data were simulated for 3226 individuals in 5 generations. Genomic data for 5 chromosomes were simulated using coalescent model. In total, the data included 10,031 SNPs, 30 additive QTLs, 2 interacting QTL pairs, and 3 imprinted loci. The density was 20 SNPs/1Mb, whereas mean linkage disequilibrium between adjacent SNPs was 0.1. One quantitative and one binary trait were simulated with heritability of 0.39-0.52 and additive correlation of 0.59. The data can be used as a benchmark for comparison of QTL mapping methods and models for genomic breeding value estimation under complex genetic architecture.