Table 2 |
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The number of enriched Go-categories are counted over all 24 clusters at a false discovery rate of 0.05 which is the default configuration of GoMiner. k-means and PCA+k-means do not show any eye specific enrichement in any of the clusters. Only LE+k-means provides one cluster that is enriched for 3 categories specific to eye development. These categories would have even been picked at an FDR of 0.01 suggesting strong statistical support for the LE+k-means performance. Potential nonlinear structures in the data could be an explanation for this observation, see Figure 13. |
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|
k-means |
PCA+k-means |
LE+k-means |
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|
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# enriched Go-categories |
55 |
17 |
27 |
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# enriched Go-categories specific to eye development |
0 |
0 |
3 |
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|
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Ehler et al. BMC Proceedings 2011 5(Suppl 2):S3 doi:10.1186/1753-6561-5-S2-S3 |
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