Table 5

Proportion of explained variability for the genetic factors contributing to CAC^a (by visit)

Factor

L1^b

L2

Factor

Visit

Mean

(Min - Max)

Mean

(Min - Max)

Mean

(Min - Max)

ME

1

0.0053

0.0037 - 0.0065

0.00002

0.0^c - 0.00012

0.00030

0.00008 - 0.00063

2

0.0092

0.0075 - 0.0112

0.00003

0.0 - 0.00013

0.00055

0.00015 - 0.00093

3

0.0115

0.0091 - 0.0137

0.00003

0.0 - 0.00019

0.00066

0.00027 - 0.00127

PE

1

0.0091

0.0076 - 0.0115

0.00004

0.0 - 0.00020

0.00003

0.0 - 0.00014

2

0.0176

0.0152 - 0.0212

0.00004

0.0 - 0.00017

0.00004

0.0 - 0.00019

3

0.0226

0.0191 - 0.0266

0.00004

0.0 - 0.00021

0.00004

0.0 - 0.00016

Het

1

0.0021

0.0012 - 0.0032

2

0.0045

0.0032 - 0.0060

3

0.0062

0.0045 - 0.0080

^aModels included the genetic factors age, sex, CHOL, and HDL.

^bColumns L1 and L2 indicate the effect of each of the epistatic loci when analyzed without its mate.

^c0.0 indicates R²<10^-5

Kraja et al. BMC Proceedings 2009 3(Suppl 7):S4