Table 1 |
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|
Genomic regions and candidate genes identified for case-control study of rheumatoid arthritis in GAW16 |
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|
Chromosome |
Genomic region (Mb) |
SNP with the largest effect |
Number of genes |
Candidate genes |
|
|
||||
|
6p21.33 |
31.55-31.62 |
rs2523647 |
4 |
MICB-001; MICB-002; MCCD1-001; BAT1 |
|
6p21.32 |
32.33-32.41 |
rs10484560 |
1 |
C6orf10 |
|
6p21.32 |
32.47-32.69 |
rs3135363 |
6 |
BTNL2; HLA-DRA; AL662796.6; HLA-DRB9; HLA-DRB5; HLA-DRB1 |
|
6p21.32 |
37.74-32.79 |
rs9275601 |
1 |
HLA-DQB1 |
|
6p21.32 |
32.87-32.97 |
rs9380326 |
5 |
HLA-DOB; TAP2; PSMB8; PSMB9; TAP1 |
|
6p21.32 |
33.21-33.29 |
rs3130237 rs6901221 |
5 |
COL11A2; RXRB; SLC39A7; HSD17B8; RING1 |
|
9q33.1 |
12.05-12.12 |
rs2900180 |
3 |
DBC1; TRAF1a; C5a |
|
10q11.22 |
49.64-49.79 |
rs2671692 |
2 |
C10orf64; LRRC18 |
|
18q12.1 |
26.82-26.88 |
rs2852003 |
1 |
DSC3 |
|
|
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|
aThe identified SNPs are in linkage disequilibrium with these genes. |
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|
Zhang et al. BMC Proceedings 2009 3(Suppl 7):S17 |
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