Table 1

Type I error rates and power (in percentage) for testing association in the presence of linkage (T1)

LD group (number of SNPs)


Significance level (%)

r2 = 0 (n = 947)

0 <r2 <= 0.01 (n = 1751)

0.01 <r2 <= 0.1 (n = 304)

0.1 <r2 <= 0.3 (n = 29)

0.3 <r2 <= 0.92 (n = 18)


FBAT-e

5

4.9

29.1

90.4

100

100

1

1

18.4

85.3

100

100

0.1

0.1

10.4

77.2

99.9

100

Millstein-b

5

4.9

28.6

90.1

100

100

1

1

18

84.9

100

100

0.1

0.1

10.1

76.6

99.9

100

LAMP-LE

5

4.3

22.5

87.8

100

100

1

0.9

14.3

81.8

100

100

0.1

0.1

8.2

73.4

99.8

100

TDT

5

5.1

29.9

90.7

100

100

1

1.1

19.1

85.9

100

100

0.1

0.1

11

78.1

99.9

100

HST-LE

5

5.2

5.9

21.3

49.9

86.9

1

1.1

1.4

10.3

41.8

79.5

0.1

0.1

0.2

4.1

34.1

74.9

HSTDT

5

7.3

29.2

90.2

100

100

1

1.9

18.6

85.3

100

100

0.1

0.3

11

77.9

99.8

100


Chen et al. BMC Proceedings 2007 1(Suppl 1):S38  

Open Data