Table 2 |
||||||
|
Results of using different distance criterion to define cis regulators |
||||||
|
3 Mb |
10 Mb |
20 Mb |
||||
|
|
|
|
||||
|
Parameter |
cis (<) |
trans (≥) |
cis (<) |
trans (≥) |
cis (<) |
trans (≥) |
|
|
||||||
|
No. tests |
9,699 |
3,845,729 |
29,827 |
3,825,601 |
52,853 |
3,802,575 |
|
|
87.68 |
95.05 |
89.32 |
95.08 |
89.62 |
95.11 |
|
Framework I, α = 0.0001 |
||||||
|
No. rejections |
69 |
7,974 |
204 |
7,839 |
302 |
7,741 |
|
|
1.23 |
4.58 |
1.31 |
4.64 |
1.57 |
4.67 |
|
E [No. false positives] |
1 |
365 |
3 |
363 |
5 |
361 |
|
Framework II, γ = 0.05 |
||||||
|
No. rejections |
200 |
8,398 |
519 |
8,113 |
761 |
7,927 |
|
E [No. true positives] |
190 |
7,978 |
493 |
7,707 |
723 |
7,531 |
|
Framework III, R = 2,000 |
||||||
|
Rejection without stratification |
29 |
1971 |
90 |
1,910 |
127 |
1,873 |
|
Rejection with stratification |
67 |
1933 |
184 |
1,816 |
222 |
1,778 |
|
Overall |
2.03 |
1.99 |
1.99 |
|||
|
|
||||||
|
Huang et al. BMC Proceedings 2007 1(Suppl 1):S142 |
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