Table 1 |
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|
Type I error and power |
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|
Type I errora |
Powerb |
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|
|
|
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|
Method |
0.05 |
0.005 |
0.0005 |
Chr 6 |
Chr 11 |
Chr 18 |
|
|
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|
Single-SNP association |
0.051 |
0.0048 |
0.00057 |
1.0 |
0.7 |
0.1 |
|
Haplotype association |
0.053 |
0.0052 |
0.00051 |
1.0 |
0.8 |
0.1 |
|
HSS |
0.052 |
0.0046 |
0.00031 |
1.0 |
1.0 |
0.1 |
|
CROSS |
0.051 |
0.0051 |
0.00061 |
1.0 |
1.0 |
0.4 |
|
|
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|
aType I results at three different significance levels were determined from the Replicates 1 to 10 of SNPs on all chromosomes except 6, 11, and 18. bPower is determined as the fraction of replicates showing a significant result (p < 0.05/9187) in a 1-Mb region around SNP6_153 on chromosome 6, SNP11_389 on chromosome 11, and SNP18_269 on chromosome 18. |
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|
Nolte et al. BMC Proceedings 2007 1(Suppl 1):S129 |
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