Evolution of the objective function during optimization. Increase in the value of the objective function (number of mutants captured) during DE runs with population size N = 19. Pink line: Model performance for the initial guess for the parameter vector (O = 72 hits; Omax = 119). Green and blue lines: Number of mutants captured in two independent DE runs with the same initial population of 19 parameter vectors. Different random number sequences in mutation and crossover operations in these runs.
Oguz et al. BMC Systems Biology 2013 7:53 doi:10.1186/1752-0509-7-53