Figure 2.

First step of the optimization: Latin Hypercube sampling. Feasible and infeasible parameter vectors during LH sampling (green and black dots), and the starting point of the parameter search (red dot). This is a projection of the whole parameter space onto the axes of two model parameters (basal Pds1 synthesis and basal Cdc15 inactivation rates).

Oguz et al. BMC Systems Biology 2013 7:53   doi:10.1186/1752-0509-7-53
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