Resolution:
## Figure 3.
Pearson correlation coefficients for each pair of reactions. (a) Cycles, pathways and homogeneous reaction groups are reported sideways, the compartment
is reported at the bottom. Neuron and astrocyte sector also include transports from/to
the cell, while the extra/intercellular class groups reactions that either directly
connect neuron to astrocyte, or involve only extracellular compartments. Null fluxes
are represented in white. Above the diagonal we report the Pearson’s coefficients
obtained by imposing V_{cyc} = 0, while below the diagonal V_{cyc} is allowed to assume positive values. (b,c,d) Histograms of the Pearson correlation coefficients for each pair of reactions within
neurons (b), astrocytes (c) or between cells (d). For each plot, the distributions are reported for V_{cyc} = 0 (in pale blue) and V_{cyc} > 0 (transparent). Null fluxes (i.e. those fluxes that are plotted in white in panel
(a)) are excluded from the histograms. Apart of the apparent larger number of null fluxes
with V_{cyc} = 0, the histograms show that the bins at higher correlation tend to be more populated
at V_{cyc} > 0 than at V_{cyc} = 0, while the opposite holds for central bins (i.e. those bins with very low direct
or inverse correlation).
Massucci |