Figure 3.

Core network of CPP differential urine metabolites. Gray boxes represent distinct pathways: (A) Tyrosine metabolism; (B) Tryptophan metabolism; (C) Arginine and proline metabolism; (D) Taurine and hypotaurine metabolism; (E) Alanine, aspartate and glutamate metabolism; (F) Pyrimidine metabolism. Abbreviations: HPG, hypothalamic pituitary gonadal; HPA, hypothalamic pituitary adrenal; CRH, corticotropin releasing hormone; GnRH, gonadotropin releasing hormone; ACTH, adrenocorticotropic hormone; GTH, gonadotropic hormone.