Computational results for mass functions for LV, collagen, and muscle, as well as volume fraction for collagen. These functions were used as inputs to our mathematical model. (A) The total LV mass fitted with data generated in autopsy experiments; (B) Collagen temporal profile fitted with known trend from experiments; (C) Temporal profile of muscle mass calculated as the difference between total and collagen mass; (D) Volume fraction of collagen, the values for young (6-9 months) and senescent (>25 months) were obtained from published results of mouse.
Yang et al. BMC Systems Biology 2012 6(Suppl 3):S10 doi:10.1186/1752-0509-6-S3-S10