Table 8

Summary of number of pathways, average number of genes per pathway and average number of gene pairs per pathway before and after integration.

H. sapiens

No. of Pathways BEFORE integration

Average No. of genes/pathway

Average No. of gene pairs/pathway


WikiPathways

135 pathways

46.3

166.2

HumanCyc

290 pathways

7.2

33.0

KEGG

237 pathways

72.4

171.3


H.sapiens

No. of unique PathwaysAFTER integration

Average No. of genes/pathway

Average No. of gene pairs/pathway


WikiPathways

100 pathways

42.7

157.4

HumanCyc

225 pathways

7.2

31.6

KEGG

201 pathways

72.6

165.3

Integrated Pathways

57 pathways

59.5

263.6


M.musculus

No. of Pathways BEFORE integration

Average No. of genes/pathway

Average No. of gene pairs/pathway


WikiPathways

140 pathways

57.8

209.1

MouseCyc

323 pathways

8.0

61.4

KEGG

218 pathways

74.6

194.8


M.musculus

No. of unique Pathways AFTER integration

Average No. of genes/pathway

Average No. of gene pairs/pathway


WikiPathways

97 pathways

56.8

242.8

MouseCyc

204 pathways

7.4

43.0

KEGG

172 pathways

77.9

187.3

Integrated Pathways

85 pathways

52.6

260.9


S.cerevisiae

No. of Pathways BEFORE integration

Average No. of genes/pathway

Average No. of gene pairs/pathway


WikiPathways

125 pathways

11.8

0.5

YeastCyc

184 pathways

6.5

13.4

KEGG

98 pathways

35.2

34.7


S.cerevisiae

No. of unique Pathways AFTER integration

Average No. of genes/pathway

Average No. of gene pairs/pathway


WikiPathways

45 pathways

15.1

0.2

YeastCyc

85 pathways

5.8

11.6

KEGG

80 pathways

38.0

35.0

Integrated Pathways

76 pathways

14.1

25.2


M.tuberculosisH37Rv

No. of Pathways BEFORE integration

Average No. of genes/pathway

Average No. of gene pairs/pathway


WikiPathways

8 pathways

22.3

7.8

MTBRvCyc

234 pathways

5.7

18.9

KEGG

110 pathways

32.5

47.5


M.tuberculosisH37Rv

No. of unique Pathways AFTER integration

Average No. of genes/pathway

Average No. of gene pairs/pathway


WikiPathways

0 pathways

MTBRvCyc

171 pathways

5.9

21.0

KEGG

94 pathways

35.4

51.7

Integrated Pathways

35 pathways

12.3

25.4


The table below shows the number of pathways from major pathway databases before and after integration.

Zhou et al. BMC Systems Biology 2012 6(Suppl 2):S2   doi:10.1186/1752-0509-6-S2-S2

Open Data