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This article is part of the supplement: Proceedings of the 23rd International Conference on Genome Informatics (GIW 2012)

Open Access Proceedings

MicroRNA 3' end nucleotide modification patterns and arm selection preference in liver tissues

Sung-Chou Li1, Kuo-Wang Tsai2, Hung-Wei Pan2, Yung-Ming Jeng3, Meng-Ru Ho4 and Wen-Hsiung Li145*

Author Affiliations

1 Genomics Research Center, Academia Sinica, Taipei, Taiwan

2 Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan

3 Graduate Institute of Pathology, National Taiwan University, Taipei, Taiwan

4 Biodiversity Research Center, Academia Sinica, Taipei, Taiwan

5 Department of Ecology and Evolution, University of Chicago, Chicago, IL 60637, USA

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BMC Systems Biology 2012, 6(Suppl 2):S14  doi:10.1186/1752-0509-6-S2-S14

Published: 12 December 2012

Additional files

Additional File 1:

RNA classes of the sequence reads in libraries. We first mapped the sequence reads back to pre-miRNAs, followed by mapping the non-miRNA reads back to different datasets for identifying their RNA categories.

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Open Data

Additional File 2:

Expression of Dorsha and Dicer in HCV-positive and HCV-negative samples. Reverse transcription-polymerase chain reaction (RT-PCR) was used to determine the mRNA levels of Dicer and Drosha in HCCs with hepatitis C virus (HCV) infection or not and their non-tumor liver samples. ribosomal protein S26 was used as internal control.

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Open Data

Additional File 3:

The mapping result of all miRNA reads in all libraries.

Format: PDF Size: 5.4MB Download file

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Open Data