Our analytic workflow to identify biomarkers for acupuncture treatment effect. Metabolite profiles are originally generated by 1H NMR from control samples and the samples with acupuncture treatment. Then we develop a linear programming based feature selection method to compare the two groups of metabolite profiles. Finally a small set of metabolites are selected as biomarkers for acupuncture effect.
Wang et al. BMC Systems Biology 2012 6(Suppl 1):S15 doi:10.1186/1752-0509-6-S1-S15