Figure 18 .

Heatmap of an adjacency matrix connecting 53 cancer drugs and 32 severe side-effects. Statistical interactions between cancer drugs: light green (nā€‰=ā€‰19) are drugs that target cell signalling components, and dark green (nā€‰=ā€‰34) are cytotoxic drugs; as well as 32 severe side-effects (purple) and drugs/side-effects interactions (orange) created from patient records (rows) from the AERS database applying the network inference method on the most recent 50,000 entries. Color intensity represents the strength of the link. Drugs and side-effects are hierarchically clustered separately.

Clark et al. BMC Systems Biology 2012 6:89   doi:10.1186/1752-0509-6-89
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