A sub-network from the human cancer combinatorial gene regulatory network composed of regulators only. Pink nodes indicate miRNAs; blue and grey nodes indicate TFs regulating or not regulating other regulators. Regulation relationships are differentially designated with three different edges according to the linear regression p-value: solid lines (most credible, p < 0.01), dashed line (medium credible, 0.01 < p < 0.05), and dotted line (less credible, p > 0.05). Numbers tagged with each edge are the T-statistics of the corresponding regulation.
Yu et al. BMC Systems Biology 2012 6:61 doi:10.1186/1752-0509-6-61