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Open Access Research article

Genome-scale metabolic model of the fission yeast Schizosaccharomyces pombe and the reconciliation of in silico/in vivo mutant growth

Seung Bum Sohn12, Tae Yong Kim12, Jay H Lee4 and Sang Yup Lee123*

Author Affiliations

1 Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering (BK21 program), Center for Systems and Synthetic Biotechnology, Institute for the BioCentury, KAIST, Daejeon, Republic of Korea

2 Bioinformatics Research Center, KAIST, Daejeon, Republic of Korea

3 Department of Bio and Brain Engineering and Bioinformatics Research Center, KAIST, Daejeon, Republic of Korea

4 Department of Chemical and Biomolecular Engineering (WCU Program), KAIST, Daejeon, Republic of Korea

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BMC Systems Biology 2012, 6:49  doi:10.1186/1752-0509-6-49

Published: 25 May 2012

Additional files

Additional file 1::

List of metabolic reactions and metabolite abbreviations used in SpoMBEL1693.

Format: PDF Size: 145KB Download file

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Open Data

Additional file 2::

SpoMBEL1693 Characteristics and biomass composition.

Format: PDF Size: 46KB Download file

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Open Data

Additional file 3::

Additional validation studies for SpoMBEL1693 - Carbon source utilization and Flux Variability Analysis of ethanol production capacity.

Format: PDF Size: 108KB Download file

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Open Data

Additional file 4::

List of False positive and False negative predictions from single knockout simulation using SpoMBEL1693.

Format: PDF Size: 29KB Download file

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Open Data

Additional file 5::

SpoMBEL1693 in SBML format.

Format: XML Size: 1.2MB Download file

Open Data