|Metabolic fluxes in the network model used for data simulation|
|Flux||Wild type (WT)||PC cells (PYC)|
|Gluc.ext → G6P||1.00||1.00|
|G6P → R5P + CO2||0.29||0.08|
|GAP → Pyr||1.88||1.93|
|Pyr → Lac||0.95||0.30|
|OAC + AcCoA → AKG + CO2||0.89||1.88|
|Pyr + CO2 → OAC||0.00||0.84|
|Mal → OAC||0.89||1.10|
|Mal → Pyr + CO2||0.15||1.11|
Fluxes were taken from Henry et al. and were normalized to glucose uptake. Fluxes are shown for wild-type HEK-293 cells (WT) and HEK-293 cells expressing yeast pyruvate carboxylase (PYC).
Crown et al.
Crown et al. BMC Systems Biology 2012 6:43 doi:10.1186/1752-0509-6-43