The effect on of hemizygous deletions on progress through the cell cycle. The percentage of cells in G1 phase of the cell cycle during exponential growth is shown on the vertical axis for 120 heterozygous deletion mutants. The mean length of G1 as a percentage of the total length of the cell cycle is shown for all strains (bars show ± 1 standard deviation from the mean). The HO/ho mutant strain used as a control is shown in blue. Strains showing changes in the cell cycle > 1 sd and significant haploproficiency (P < 0.001) in one or more of the D > = 0.3 h-1 experiments are highlighted in red, along with cyclin gene CLB2, which does not show haploproficiency, but shows a strong cell cycle phenotype.
Pir et al. BMC Systems Biology 2012 6:4 doi:10.1186/1752-0509-6-4