Figure 5.

Validity of the deterministic QSSA for the cooperative two-subunit enzyme network. Plot of the macroscopic substrate concentration [S] versus time, as obtained by numerically solving the deterministic REs of the full network (solid lines) and the reduced REs obtained using the deterministic QSSA (open circles). The color coding and rate constant values are as in Figure 4 (a) and (b); the value of Θis 0.5. The excellent agreement between the two RE solutions, implies timescale separation conditions

Thomas et al. BMC Systems Biology 2012 6:39   doi:10.1186/1752-0509-6-39
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