Resolution:
## Figure 2.
Determining the validity of the heuristic CME. Scheme illustrating the analytical approach to determine the validity of the heuristic
CME which is used in this article. Parameters are chosen such that the deterministic
QSSA is valid and such that molecule numbers are not too small. The LNA is applied
to the heuristic CME leading to a linear FPE, describing the noise of the slow species.
A different reduced linear FPE describing the noise in the slow species is obtained
by applying a rigorous adiabatic elimination method on the linear FPE which approximates
the CME of the full network. The noise statistics from the two linear FPEs are compared
Thomas |