Subvolume size. The model described in the text is simulated for different uniform meshes over a range of tetrahedron sizes, all within the acceptable upper and lower bound of 0.4 μm to 0.02 μm, and each mesh representing the same geometry. Mean results for 10 iterations in each case are identical for each mesh size with no errors, demonstrating the accuracy of the well-mixed approximation in this range.
Hepburn et al. BMC Systems Biology 2012 6:36 doi:10.1186/1752-0509-6-36