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Open Access Highly Accessed Research article

Genome-scale metabolic reconstructions of Pichia stipitis and Pichia pastoris and in silico evaluation of their potentials

Luis Caspeta, Saeed Shoaie, Rasmus Agren, Intawat Nookaew and Jens Nielsen*

Author Affiliations

Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden

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BMC Systems Biology 2012, 6:24  doi:10.1186/1752-0509-6-24

Published: 4 April 2012

Additional files

Additional file 1:

Composition of the human monoclonal antibody 3H6 Fab fragment (FAB) used as model recombinant protein.

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Additional file 2:

Gene orthology analysis among the three yeast species: Pichia stipitis, Pichia pastoris, and Saccharomyces cerevisiae.

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Additional file 3:

Analysis of reaction essentiality predicted by simulations.

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Additional file 4:

Maximum capacities for amino acids production among the three yeast species: Pichia stipitis, Pichia pastoris, and Saccharomyces cerevisiae.

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