Solid map on huge interactome of rhein-targets networks, built and visualized with Cytoscape. Edges: interactions. Nodes: specific proteins or genes. Central nodes (Yellow) of the interaction network were used to illustrate the gene expression obtained and represents significant change in expression. The connections between molecules show molecular interactions identified in the interactome. Gene expression illustrated in colored nodes was selected with a p < 0.05 value.
Zhang et al. BMC Systems Biology 2012 6:20 doi:10.1186/1752-0509-6-20